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The OSK-KI mouse model, generated by knocking the Osaka mutation into the endogenous mouse APP gene, displayed APP expression levels similar to those of wild-type (WT) mice

FIGURE 1 Next, to determine the neurotoxic effect of peroxynitrite on cultured SGNs, the cultured SGNs were treated with different concentrations (100 or 200 M) of peroxynitrite for 24 or 48 h, respectively (Figure 2A)

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Boosts energy levels Probably one of the most well-known reasons individuals request b12 shots for energy is due to chronic fatigue

In addition, ROS can trigger prodeath or prosurvival autophagy in cancer cells (Chen et al., 2008)